Life1000 Team

CATECHOL-O-METHYLTRANSFERASE GENE (COMT)

CATECHOL-O-METHYLTRANSFERASE GENE (COMT)

What does this gene do? Warrior or worrier? The COMT gene plays an important role in the nervous system as it is important in regulating chemicals in the brain such as dopamine and adrenaline. It does this by deactivating these chemicals by adding a methyl group (CH3) to them, another example of this important process called methylation which is a common on/off switch used in the body. If lots of ...[Read More]

MANGANESE SUPEROXIDE DISMUTASE GENE (MNSOD)

MANGANESE SUPEROXIDE DISMUTASE GENE (MNSOD)

What does this gene do? Manganese Superoxide Dismutase is a gene that encodes for a protein found in the energy powerhouse inside of our cells, called the mitochondria. This enzyme acts as a major antioxidant meaning it plays a critical role in protecting cells from stress and damage. Stress in the human body, like rust in a car, is responsible for damage caused to cells and DNA. This damage is ca ...[Read More]

GLUTATHIONE S-TRANSFERASE-T GENE (GSTT1)

GLUTATHIONE S-TRANSFERASE-T GENE (GSTT1)

What does this gene do? This gene is part of the GST family, which play an important role in the detoxification process of a number of compounds. Effectively it helps to make powerful substances that are consumed or in the environment, less toxic by making them water soluble meaning they can be excreted easily by the body (by obvious means) Specific natural chemicals found in cruciferous vegetable ...[Read More]

QUINONE REDUCTASE GENE (NQO1)

QUINONE REDUCTASE GENE (NQO1)

What does this gene do? Quinone Oxidoreductase 1 (NQO1) gene is a member of the NAD(P)H dehydrogenase (quinone) family.  NQO1 plays an important role in getting rid of toxins often referred to as “detoxification”. Due to the detoxification ability of this gene, it is considered to be important in protection of cells, proteins, DNA and other molecules from damage caused by harmful subst ...[Read More]

ALPHA-ACTININ 3 GENE (ACTN3) 577 R/X

ALPHA-ACTININ 3 GENE (ACTN3) 577 R/X

What does this gene do? The ACTN3 gene is active in muscle.  Alpha-actin is only found in fast twitch muscle fibres which are responsible for fast muscle movements such as in the case of sprinting. The variant that is of impact is the C allele. If you have a two “Cs” as your result you’re more likely to achieve improvements in strength, speed and power in training. You see this result ...[Read More]

COLLAGEN TYPE 1 ALPHA 1 GENE (COL1A1)

COLLAGEN TYPE 1 ALPHA 1 GENE (COL1A1)

What does this gene do? This COL1A1 gene codes for the protein that makes collagen. Collagen1 is the most abundant in the body. It’s the main collagen found in joint cartilage, skin, tendon, ligaments and bone. When there are variants found in COL1A1 gene it’s linked to the risk of soft tissue injuries. These injuries can include achilles tendinopathy/rupture and shoulder dislocation.  COL1A1 vari ...[Read More]

FAT MASS AND OBESITY ASSOCIATED GENE (FTO)

FAT MASS AND OBESITY ASSOCIATED GENE (FTO)

What does this gene do?  The fat mass and obesity associated (FTO) gene, also known as the “Fat gene” was the first obesity-susceptibility gene identified  by a particular research method, however there are currently over 90 genes that have been associated with risk of obesity. The FTO gene is plays a role in managing your energy balance and has also been found to regulate how (and whe ...[Read More]

ANGIOTENSIN 1 CONVERTING ENZYME GENE (ACE)

ANGIOTENSIN 1 CONVERTING ENZYME GENE (ACE)

What does this gene do? The Angiotensin 1 converting enzyme (ACE) gene plays an important role managing your blood pressure. This system is known as renin-angiotensin system (RAS). It regulates blood pressure by managing how much or little your blood vessels stiffen or relax depending on the amount body salts such as sodium and potassium in your blood. Sodium (a component of table salt)  is one of ...[Read More]

BETA2-ADRENERGIC RECEPTOR GENE (ADRB2)

BETA2-ADRENERGIC RECEPTOR GENE (ADRB2)

What does this gene do? The ADRB2 gene plays a role in fat cells, it controls the breakdown and release of fat used for energy. It’s involved in this energy regulation and determines how well you fat- burning ability during and following exercise The variants of ADRB2 have been linked to an increased risk of obesity and responding slowly to weight loss attempts. Limited available research have fou ...[Read More]

MELATONIN 1 RECEPTOR (MC1R)

MELATONIN 1 RECEPTOR (MC1R)

What does this gene do? The MC1R gene codes for making the protein called the melanocortin 1 receptor. The receptor functions as part of the normal pigmentation (or tanning) process. The receptor is mainly found on the surface of skin cells (melanocytes), these are specialised cells that produce a pigment or colouring known as melanin. Melanin is the pigment that gives hair, eyes and skin their co ...[Read More]

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